Materials Science and Technology of Polymers at the University of Twente

Lecture Prize for Denis Dorokhin

His lecture describes derivatization of semiconductor QDs with stimuli responsive ligands such as ferrocene thios. By choosing a proper coating for the QDs, one is able to tune and control the luminescence and physicochemical properties of the nanoparticles. In this contribution we describe the synthesis, luminescence properties, and phase transfer of ferrocene-coated CdSe/ZnS QDs, where modified fluorescent nanoparticles form a host-guest complex with B-cyclodextrin (B-CD) oligosaccharides. This complex becomes soluble in biologically relevant enviroments and the QDs transffered from organic into aqueous phase become carriers of biomolecules in the new media. The host-guest interaction between ferrocene and B-CD can be reversed upon oxidation or upon addition of molecules having higher binding constant to the B-CD cavity, e.g. adamantane or naphtalene derivatives.